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Updated: Jun 29, 2025

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
Published on: November 8, 2012
White matter tracts adjacent to the human cingulate sulcus visual area (CSv)
Maiko Uesaki1,2,3, Michele Furlan4, Andrew T Smith5
1Center for Information and Neural Networks (CiNet), Advanced ICT Research Institute, National Institute of Information and Communications Technology (NICT), Suita, Osaka, Japan.
The human cingulate sulcus visual area (CSv) connects to major white matter tracts, including the superior longitudinal fasciculus (SLF I) and cingulum, aiding self-motion processing.
Area of Science:
- Neuroscience
- Human brain mapping
- Visual processing
Background:
- The human cingulate sulcus visual area (CSv) is involved in processing self-motion cues.
- Understanding CSv's structural connectivity is crucial for elucidating its role in navigation and sensorimotor integration.
- Previous research identified CSv connections with motor and sensorimotor regions.
Purpose of the Study:
- To investigate the relationship between CSv and adjacent white matter tracts.
- To map CSv's structural connectivity onto known white matter pathways.
- To clarify CSv's role as a potential interface between sensory and motor systems.
Main Methods:
- Re-analysis of diffusion-weighted magnetic resonance imaging (dMRI) data from a previous study.
- Whole-brain tractography to identify fiber bundles (streamlines) connecting to CSv.
- Classification of identified streamlines based on established white matter tract anatomy.
Main Results:
- A significant portion of CSv streamlines were identified as belonging to the superior longitudinal fasciculus (SLF I) and the cingulum.
- These findings map CSv connectivity onto major white matter tracts involved in sensorimotor functions.
- The results support CSv's role in integrating self-motion information.
Conclusions:
- CSv is structurally connected to the SLF I and cingulum, major white matter tracts.
- These connections suggest CSv acts as a crucial interface between sensory input and motor systems for self-motion.
- Further research can explore the functional implications of these anatomical links for navigation.
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