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Updated: May 11, 2026

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
Published on: October 24, 2018
Intravascular guide wire aspiration in a patient on extracorporeal membrane oxygenation: A case report
Jae Ho Choi1, Jae Hwa Yoo2, Won Ho Chang1
1Department of Thoracic and Cardiovascular surgery, Soonchunhyang University Hospital Seoul, Seoul, Republic of Korea.
Rationale:
Guide wire aspiration during central venous catheter (CVC) insertion in a patient on extracorporeal membrane oxygenation (ECMO) is a very rare but dangerous complication. A guide wire aspirated inside the ECMO can cause thrombosis, the ECMO to break down or shut off, and unnecessary ECMO replacement.
Patient Concerns:
A 58-year-old man was scheduled for venovenous ECMO for acute respiratory distress syndrome. After his vital signs stabilized, we inserted a CVC. During CVC insertion, the guide wire was aspirated into the ECMO venous line.
Intervention:
After confirming the guide wire inside the ECMO venous line, we replaced the entire ECMO circuit.
Outcomes:
ECMO was maintained for 57 days, and weaning was successful but the patient died 5 days afterward.
Lessons:
Care must be taken when inserting a CVC using a guide wire in ECMO patients: the guide wire should not be inserted deeply, it should be secured during insertion, the ECMO venous cannula tip requires proper positioning, and ECMO flow should be temporarily reduced.
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