EBER-negative inflammatory pseudotumor-like follicular dendritic cell sarcoma of liver: A case report
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View abstract on PubMed
Summary
This summary is machine-generated.Inflammatory pseudotumor-like follicular dendritic cell sarcoma (IPT-like FDCS) is a rare liver tumor. Diagnosis should not solely rely on Epstein-Barr virus (EBV) positivity, as EBV-negative cases exist.
Area Of Science
- Oncology
- Pathology
- Hepatology
Background
- Inflammatory pseudotumor-like follicular dendritic cell sarcoma (IPT-like FDCS) of the liver is a rare entity.
- Historically, Epstein-Barr virus (EBV) positivity was considered essential for diagnosis.
- Recent findings suggest EBV negativity does not exclude IPT-like FDCS.
Observation
- A 70-year-old female presented with upper abdominal discomfort and a progressively enlarging liver tumor.
- Imaging (CT, MRI) and histopathological analyses (HE, immunohistochemistry) were performed.
- The patient underwent laparoscopic left hemihepatectomy for the liver tumor.
Findings
- The final diagnosis was IPT-like follicular cell sarcoma.
- The patient's tumor was EBV-negative.
- No adjuvant therapy (radiotherapy, chemotherapy) was administered post-surgery.
Implications
- EBV positivity is not a mandatory criterion for diagnosing IPT-like FDCS.
- Pathologists should consider EBV-negative IPT-like FDCS, particularly in liver cases.
- Accurate pathological assessment remains crucial for diagnosing this rare liver sarcoma.
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