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Updated: Jun 29, 2025

Generation of CAR T Cells for Adoptive Therapy in the Context of Glioblastoma Standard of Care
Published on: February 16, 2015
Severe Visual Impairment Following CAR T-Cell Therapy in Two Individuals with Malignant Optic Nerve Infiltration
Pierre-Maurice Herr, Victor Brantl1, Siegfried Georg Priglinger1
1Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany.
Abstract:
We report two patients who displayed evidence of localized ocular inflammation after CAR T-cell infusion. To manage the resulting severe visual impairment, systemic corticosteroids were administered to both patients. This treatment led to a reduction in local inflammation and restored vision in one of the patients.
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