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Identification of benzo[b]thiophene-1,1-dioxide derivatives as novel PHGDH covalent inhibitors

Xin-Yu Cao1, Xinge Li2, Feng Wang1

  • 1The Research Center of Chiral Drugs, Shanghai Frontiers Science Center for TCM Chemical Biology, Innovation Research Institute of Traditional Chinese Medicine,Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

Bioorganic Chemistry
|April 5, 2024
PubMed

Keywords:
AntitumorCovalent inhibitorPHGDHSerine synthesis pathwayStattic

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