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Multimodal 3D Printing of Phantoms to Simulate Biological Tissue
Published on: January 11, 2020
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4D Printing for Biomedical Applications
Ebrahim Yarali1,2, Mohammad J Mirzaali1, Ava Ghalayaniesfahani1,3
1Department of Biomechanical Engineering, Faculty of Mechanical Engineering, Delft University of Technology (TU Delft), Mekelweg 2, Delft, 2628 CD, The Netherlands.
Advanced Materials (Deerfield Beach, Fla.)
|April 5, 2024
Summary
4D (bio-)printing creates dynamic biomedical devices with multiple functionalities. This review covers smart materials, stimuli, design, and biomedical applications, exploring future research directions for advanced medical innovations.
Area of Science:
- Biomedical Engineering
- Materials Science
- Additive Manufacturing
Background:
- 4D (bio-)printing enhances 3D printed materials with dynamic properties and functionalities.
- Applications include stents, drug delivery systems, and implantable medical devices.
Purpose of the Study:
- To review smart materials, stimuli, and design strategies in 4D (bio-)printing.
- To critically assess current biomedical applications of 4D printing.
- To discuss future research directions in the field.
Main Methods:
- Highlighting various smart materials and external stimuli used in 4D (bio-)printing.
- Reviewing design strategies for 4D printed objects.
- Analyzing current biomedical applications and future trends.
Main Results:
- 4D printing enables the creation of functional and dynamic biomedical devices.
- Success depends on rational design, smart material selection, and appropriate stimuli.
- Future research includes in vivo studies, multi-material integration, and advanced modeling.
Conclusions:
- 4D (bio-)printing offers significant potential for advanced biomedical applications.
- Further research is needed in areas like in vivo regeneration, multi-material systems, and predictive modeling.
- The field is rapidly evolving with potential for transformative medical devices.
