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Effectiveness of a cognitive behavioral therapy-integrated, hospital-based program for prediabetes: a matched cohort

Chaiwat Washirasaksiri1, Withada Pakornnipat2, Pinyapat Ariyakunaphan1

  • 1Division of Ambulatory Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wang Lang Road, Bangkok Noi, Bangkok, 10700, Thailand.

Scientific Reports
|April 5, 2024
PubMed

Insights

A hospital-based diabetes prevention program integrating cognitive behavioral therapy (CBT) significantly reduced type 2 diabetes (T2DM) progression in prediabetes patients. This intervention halved the risk of developing T2DM over 60 months.

Area of Science:

  • Metabolic Health
  • Behavioral Medicine
  • Clinical Research

Background:

  • Intensive lifestyle interventions are proven for type 2 diabetes (T2DM) prevention.
  • Evidence for hospital-based programs in high cardiometabolic risk individuals is limited.
  • Prediabetes management is crucial to prevent T2DM.

Purpose of the Study:

  • To evaluate a hospital-based diabetes prevention program integrating cognitive behavioral therapy (CBT).
  • To assess the long-term effectiveness of this intervention in individuals with prediabetes.
  • To compare T2DM incidence between the intervention and standard care groups.

Main Methods:

  • A matched cohort study comparing a 1-year CBT-integrated prevention program with standard care.
  • Kaplan-Meier and Cox regression models analyzed 60-month T2DM incidence.
  • Participants had prediabetes and high cardiometabolic risk.

Main Results:

  • The intervention group showed significant decreases in fasting plasma glucose, HbA1c, triglycerides, and weight after 12 months.
  • At 60 months, the T2DM incidence rate was 1.7 in the intervention group versus 3.5 in the standard-care group.
  • The intervention group had a 0.46 times lower adjusted risk of developing T2DM.

Conclusions:

  • Hospital-based diabetes prevention programs integrating CBT are effective in reducing T2DM progression.
  • This intervention significantly lowers the risk of developing type 2 diabetes in prediabetes patients.
  • Healthcare providers should promote such integrated programs for diabetes prevention.

Keywords:
Cognitive behavioral therapyHigh cardiometabolic riskPrediabetic statePreventive programThai

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