Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reliability and validity of the individual GPS game data-based maximal acceleration-initial running speed regression line in youth elite soccer players.

PloS one·2026
Same author

Persistent choroidal folds in myelin oligodendrocyte glycoprotein antibody-associated disease.

Multiple sclerosis and related disorders·2026
Same author

Serum Glial Fibrillary Acidic Protein and Retinal Neuronal Loss as Additive Prognostic Markers of Disability in Multiple Sclerosis.

Neurology(R) neuroimmunology & neuroinflammation·2026
Same author

Satisfactory Visual Outcome after IC-8 Intraocular Lens Implantation in a Patient with Keratoconus.

Klinische Monatsblatter fur Augenheilkunde·2026
Same author

Case Report: Progressive visual decline after optic neuritis associated with microcystic macular oedema.

Frontiers in neurology·2026
Same author

Improving longitudinal performance assessment of youth soccer players: 10 m sprint percentile curves adapted to biological age.

Science & medicine in football·2026

Related Experiment Video

Updated: Jun 29, 2025

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

1.6K

Swiss Multicenter Ab Interno XEN45 Gel Stent Study: 2-Year Real-World Data.

Anthia Papazoglou1,2, René Höhn3,4, Megir Schawkat3

  • 1Department of Ophthalmology, Cantonal Hospital Aarau, Aarau, Switzerland. anthia.papazoglou@gmail.com.

Ophthalmology and Therapy
|April 6, 2024
PubMed
Summary

The XEN45 Gel Stent effectively lowered intraocular pressure (IOP) and reduced the need for glaucoma medications in most patients over two years. This minimally invasive glaucoma surgery shows promising long-term results for managing eye pressure.

Keywords:
ImplantOpen angle glaucomaPseudoexfoliation glaucomaSuccess rateXEN

More Related Videos

Imaging In-Stent Restenosis: An Inexpensive, Reliable, and Rapid Preclinical Model
09:46

Imaging In-Stent Restenosis: An Inexpensive, Reliable, and Rapid Preclinical Model

Published on: September 14, 2009

13.8K
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.3K

Related Experiment Videos

Last Updated: Jun 29, 2025

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

1.6K
Imaging In-Stent Restenosis: An Inexpensive, Reliable, and Rapid Preclinical Model
09:46

Imaging In-Stent Restenosis: An Inexpensive, Reliable, and Rapid Preclinical Model

Published on: September 14, 2009

13.8K
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.3K

Area of Science:

  • Ophthalmology
  • Glaucoma Surgery
  • Medical Devices

Background:

  • Glaucoma management often requires long-term treatment to control intraocular pressure (IOP).
  • Minimally invasive glaucoma surgeries (MIGS) offer alternatives to traditional treatments.
  • The XEN45 Gel Stent is a device used in MIGS to improve aqueous humor outflow.

Purpose of the Study:

  • To evaluate the 2-year postoperative efficacy of the XEN45 Gel Stent.
  • To assess the reduction in intraocular pressure (IOP) after XEN45 implantation.
  • To determine the change in the requirement for antiglaucoma medications post-surgery.

Main Methods:

  • Retrospective, multicenter study including 345 eyes with various glaucoma types.
  • Patients received XEN45 Gel Stent implantation, with or without cataract surgery.
  • Intraocular pressure (IOP), medication use, and need for interventions were assessed at 2 years postoperatively.

Main Results:

  • A 66.0% success rate (≥20% IOP reduction) was observed at 2 years in 206 followed eyes.
  • Mean IOP decreased by 43.8% from 26.3 mmHg preoperatively to 14.8 mmHg postoperatively.
  • The average number of antiglaucoma medications reduced by 2.0 per patient, with low complication rates.

Conclusions:

  • The XEN45 Gel Stent provides significant and sustained IOP reduction 2 years postoperatively.
  • The device effectively decreases the reliance on topical hypotensive medications.
  • XEN45 Gel Stent implantation is a safe and effective option for managing various types of glaucoma.