Related Experiment Video

Updated: Jun 29, 2025

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
08:16

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model

Published on: March 16, 2022

3.5K

Risk Factors for Early Lower Limb Re-Amputation in Vascular Diseases

Diego Castro Musial1, Maria Eduardha Ligocki Irigaray2, Lauanny Caroline Gerber2

  • 1Hospital Regional Hans Dieter Schmidt, Joinville, Santa Catarina, Brazil.

Annals of Vascular Surgery
|April 6, 2024
PubMed

Insights

Dialysis, smoking, and hypertension significantly increase the risk of lower limb re-amputation within six months. Early intervention for patients with these factors is crucial to prevent repeat amputations.

Area of Science:

  • Medical research
  • Surgical outcomes
  • Public health

Background:

  • Lower limb amputations carry known risks.
  • Identifying predictors for repeat amputations is essential for patient care.
  • This study focuses on re-amputation risk within six months of the initial procedure.

Purpose of the Study:

  • To identify risk factors for re-amputation within six months of a lower limb amputation.
  • To inform early interventions for high-risk patients.

Main Methods:

  • Retrospective cohort study at a single center in Brazil (2013-2022).
  • Included 652 adult patients undergoing lower limb amputation.
  • Analyzed patient demographics, comorbidities, and amputation history using statistical tests.

Main Results:

  • 35.2% of patients required re-amputation within six months.
  • Dialysis (OR 8.36), smoking (OR 1.67), and hypertension (OR 1.55) were significant predictors of re-amputation.
  • Statistical significance was determined using Chi-squared and student's t-tests.

Conclusions:

  • Early intervention is vital for patients with identified risk factors.
  • Targeted support for dialysis, smoking, and hypertension can reduce re-amputation rates.
  • Proactive management can improve outcomes after lower limb amputation.
Abstract

More Related Videos

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia07:25

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia

Published on: September 22, 2020

3.4K
Preclinical Model of Hind Limb Ischemia in Diabetic Rabbits07:34

Preclinical Model of Hind Limb Ischemia in Diabetic Rabbits

Published on: June 2, 2019

9.7K

Related Concept Videos

Assessment of the Cardiovascular System III: Palpation01:27

Assessment of the Cardiovascular System III: Palpation

Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
323
Arteries of Lower Limbs01:20

Arteries of Lower Limbs

The external iliac artery transitions out of the body cavity, entering the femoral region of the lower leg, and is renamed the femoral artery at the point where it traverses the body wall. This artery is responsible for the distribution of blood to the thigh's deep muscles and the skin's ventral and lateral regions, achieved through several minor branches and the lateral deep femoral artery, which also spawns a lateral circumflex artery. The knee area receives blood from the genicular...
1.4K
Veins of Lower Limbs01:15

Veins of Lower Limbs

The human body consists of an intricate network of veins responsible for the crucial task of blood drainage from the lower limbs. These veins can be categorized into two main types: deep veins and superficial veins.
Formed by the union of the medial and lateral plantar veins, the posterior tibial vein, rising through the calf muscle, assimilates the fibular vein. The anterior tibial vein, a superior extension of the foot's dorsalis pedis vein, merges with the posterior tibial vein at the...
795
Pre-Procedural Guidelines for Assessing Blood Pressure01:10

Pre-Procedural Guidelines for Assessing Blood Pressure

Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the...
563