Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

327
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
327

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lymph Node Dissection of the Upper Mediastinum in Distal Oesophageal and Oesophagogastric Junction Cancer: Indicated in All Patients? Review.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2026
Same author

Institut Georges Lopez-2M as a Novel Lung Preservation Solution Attenuates Ischemia-Reperfusion Injury in a Rat <i>Ex Vivo</i> Lung Perfusion Model.

Transplant international : official journal of the European Society for Organ Transplantation·2026
Same author

A case of an incidentally discovered epithelioid haemangioendothelioma.

Journal of surgical case reports·2025
Same author

Rare Unicentric Intrapulmonary Castleman Disease: A Systematic Review and Report of a Case.

The open respiratory medicine journal·2025
Same author

Endoscopic vacuum therapy (eVAC) combined with continuous perianastomotic irrigation for prevention of anastomotic leak after surgical ampullectomy.

Langenbeck's archives of surgery·2024
Same author

Primary pulmonary meningioma: a case report.

Journal of surgical case reports·2024

Related Experiment Video

Updated: Jun 29, 2025

Author Spotlight: Enhancing Transplantation Research Through MicroCT Angiography in Murine Models
09:23

Author Spotlight: Enhancing Transplantation Research Through MicroCT Angiography in Murine Models

Published on: September 22, 2023

2.7K

Lung transplantation in children.

Jonas Peter Ehrsam1,2,3, Olga Meier Adamenko3, Manjinder Pannu4

  • 1School of Medicine, University of Zurich, Zurich, Switzerland.

Turk Gogus Kalp Damar Cerrahisi Dergisi
|April 8, 2024
PubMed
Summary

Pediatric lung transplantation offers hope for children with severe lung disease. While organ shortage is a challenge, techniques like using smaller lungs improve survival, with over 10 years possible in experienced centers.

Keywords:
Childrenlung donorlung transplantationpediatrics.

More Related Videos

Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP
06:55

Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP

Published on: February 14, 2022

1.6K
A Modified Surgical Technique for Kidney Transplantation in Mice
10:38

A Modified Surgical Technique for Kidney Transplantation in Mice

Published on: July 22, 2022

5.8K

Related Experiment Videos

Last Updated: Jun 29, 2025

Author Spotlight: Enhancing Transplantation Research Through MicroCT Angiography in Murine Models
09:23

Author Spotlight: Enhancing Transplantation Research Through MicroCT Angiography in Murine Models

Published on: September 22, 2023

2.7K
Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP
06:55

Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP

Published on: February 14, 2022

1.6K
A Modified Surgical Technique for Kidney Transplantation in Mice
10:38

A Modified Surgical Technique for Kidney Transplantation in Mice

Published on: July 22, 2022

5.8K

Area of Science:

  • Pediatric surgery
  • Thoracic transplantation
  • Pulmonology

Background:

  • Lung transplantation is a vital treatment for pediatric advanced lung disease and pulmonary vascular disorders.
  • Organ shortage presents a significant challenge in pediatric lung transplantation.
  • Techniques like using downsized adult lungs, lobes, or segments have been developed to fit children's smaller chests.

Purpose of the Study:

  • To summarize the current state of pediatric lung transplantation.
  • To highlight survival rates and challenges in pediatric lung transplant recipients.
  • To discuss factors influencing outcomes in pediatric lung transplant patients.

Main Methods:

  • Review of established pediatric lung transplantation procedures.
  • Analysis of survival data based on age, disease, and center experience.
  • Identification of key challenges in the peri- and post-transplant phases.

Main Results:

  • Worldwide median survival after pediatric lung transplantation is 5.7 years.
  • Median survival exceeding 10 years is achievable, particularly with consideration of patient age, disease, and center expertise.
  • Downsized adult lungs, lobes, or segments are successfully transplanted into children.

Conclusions:

  • Pediatric lung transplantation is a feasible treatment option for end-stage lung disease in children.
  • Optimizing referral timing and managing complications like ischemia-reperfusion injury and rejection are crucial for long-term success.
  • Further advancements are needed to overcome organ shortage and improve outcomes in pediatric lung transplant recipients.