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Updated: Jun 29, 2025

Sample Drift Correction Following 4D Confocal Time-lapse Imaging
10:04

Sample Drift Correction Following 4D Confocal Time-lapse Imaging

Published on: April 12, 2014

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Model-based frequency-and-phase correction of 1H MRS data with 2D linear-combination modeling.

Dunja Simicic1,2, Helge J Zöllner1,2, Christopher W Davies-Jenkins1,2

  • 1Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.

Biorxiv : the Preprint Server for Biology
|April 8, 2024
PubMed
Summary

A new model-based frequency-and-phase correction (FPC) method using 2D linear-combination modeling (2D-LCM) improves MR spectroscopy metabolite estimation, especially at low signal-to-noise ratios (SNR). This approach offers better accuracy and precision than traditional methods.

Keywords:
frequency-and-phase correctionmagnetic resonance spectroscopyspectral registrationtwo-dimensional linear-combination model

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