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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
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Stroke Recurrence Rate and Risk Factors Among Stroke Survivors in Sub-Saharan Africa: A Systematic Review
Scovia Nalugo Mbalinda1, Mark Kaddumukasa2, Josephine Nambi Najjuma3
1Department of Nursing, School of Health Sciences, College of Health Sciences, Makerere University, Kampala, Uganda.
Neuropsychiatric Disease and Treatment
|April 8, 2024
Summary
Stroke recurrence rates in sub-Saharan Africa are high, ranging from 9.4% to 25%. Hypertension and alcohol consumption are key risk factors, with recurrent strokes leading to higher mortality.
Area of Science:
- Neurology
- Public Health
- Epidemiology
Background:
- Secondary stroke, or stroke recurrence, is a significant concern globally.
- Limited data exists on stroke recurrence and its risk factors in sub-Saharan Africa (SSA).
Purpose of the Study:
- To systematically review and describe the incidence of stroke recurrence in sub-Saharan Africa.
- To identify associated risk factors for recurrent strokes in the SSA region.
Main Methods:
- A systematic search of scientific databases was conducted for studies published between January 2000 and December 2022.
- Population-based observational, case-control, and cohort studies involving adults in SSA were included.
- Study quality was assessed using the Critical Appraisal Skills Program (CASP) checklist.
Main Results:
- Six studies met the inclusion criteria, with stroke recurrence rates in SSA varying from 9.4% to 25%.
- Hypertension and chronic alcohol consumption were identified as primary risk factors for stroke recurrence.
- Mortality rates for recurrent strokes (20.5%–23%) were higher compared to primary strokes.
Conclusions:
- This systematic review highlights the significant burden of stroke recurrence in sub-Saharan Africa.
- Further research is needed to fully understand the outcomes and impact of recurrent strokes in SSA.
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