Related Experiment Video
Updated: Jun 29, 2025
03:24
Author Spotlight: Enhancing Candida albicans Detection in Catheter Infections Using Fluorescent Protein Tagging
Published on: March 22, 2024
1.5K
A meta-analysis of risk factors for a Dacron-cuffed catheter related infection in hemodialysis
Wen Chen1, Zaoju Wang1, Guoping Wang1
1Department of Nephrology, The First Affiliated Hospital, Gannan Medical University, Ganzhou, 341000, Jiangxi, China.
BMC Nephrology
|April 8, 2024
Summary
This study identified key risk factors for catheter-related infections (CRIs) in hemodialysis patients. Diabetes, older age, and longer catheter dwell time significantly increase CRI risk, highlighting areas for targeted prevention strategies.
Area of Science:
- Nephrology
- Infectious Diseases
- Medical Devices
Background:
- Catheter-related infections (CRIs) are a significant complication in hemodialysis patients, impacting morbidity and mortality.
- Dacron-cuffed catheters are commonly used for long-term hemodialysis access, necessitating a thorough understanding of associated infection risks.
Approach:
- A systematic literature review and meta-analysis were conducted across eight major databases.
- Included studies focused on identifying risk factors for CRIs in hemodialysis patients with Dacron-cuffed catheters.
- Meta-analysis was performed using RevMan 5.4 to determine the combined odds ratios for various risk factors.
Key Points:
- The study analyzed 13 literature pieces involving 625 patients, revealing an 11.7% infection rate.
- Significant risk factors for CRI included diabetes (OR 1.94), lower hemoglobin (OR 1.82), older age (OR 2.38), and longer catheter indwelling time (OR 1.79).
- Other critical factors were low serum albumin (OR 2.26), femoral vein catheterization (OR 3.29), and multiple catheterizations (OR 5.40).
Conclusions:
- Diabetes, low hemoglobin, advanced age, prolonged catheter use, and low serum albumin are primary risk factors for CRI in hemodialysis.
- Femoral vein catheterization and a higher number of catheterizations further elevate the risk of developing CRIs.
- These findings provide a theoretical basis for developing targeted prevention strategies to reduce CRI incidence in hemodialysis populations.
Related Concept Videos
01:26Factors Affecting the Risk of Infection
11.8K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.8K
01:27Dialysis
307
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
307