Lifestyle interventions in the management of systemic sclerosis: a systematic review of the literature
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View abstract on PubMed
Summary
This summary is machine-generated.Lifestyle interventions like physical exercise and patient education can improve physical function in systemic sclerosis (SSc) patients. These approaches complement, but do not replace, standard pharmacotherapy.
Area Of Science
- Rheumatology
- Rehabilitation Medicine
- Public Health
Background
- Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by fibrosis, vascular abnormalities, and immune system dysregulation.
- Management of SSc often involves pharmacotherapy, but lifestyle interventions are increasingly recognized for their potential to improve patient outcomes.
- Evidence regarding the efficacy of various lifestyle modifications in SSc management remains fragmented.
Purpose Of The Study
- To systematically investigate the effectiveness of lifestyle interventions for managing systemic sclerosis (SSc).
- To synthesize findings from studies evaluating physical exercise, patient education, diet, and nutrition in SSc patients.
Main Methods
- A comprehensive literature search was conducted across major databases (MEDLINE, Embase, Web of Science, CINAHL) up to June 2021.
- Included studies involved five or more SSc patients and focused on lifestyle interventions, excluding systematic reviews without meta-analyses.
- Critical appraisal of included studies was performed using Joanna Briggs Institute tools, with 36 studies selected for full-text review.
Main Results
- Seventeen studies focused on physical exercise, and 14 on educational interventions for mental health, often incorporating exercise.
- Physical exercise and patient education demonstrated positive effects on physical function, particularly hand and mouth mobility.
- Limited studies on diet and nutrition yielded insufficient evidence to draw conclusions regarding gastrointestinal or anthropometric outcomes.
Conclusions
- Physical exercise and patient education are recommended as adjuncts to pharmacotherapy for enhancing physical function in SSc.
- These lifestyle interventions should not be considered a substitute for conventional medical treatment.
- Future research should explore the impact of reducing harmful exposures (smoking, alcohol), improving sleep, and enhancing social relations in SSc management.
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