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Updated: Jun 29, 2025

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Surgical options for atrial fibrillation treatment during concomitant cardiac procedures
Massimo Baudo1, Fabrizio Rosati1, Elisabetta Lapenna2
1Department of Cardiac Surgery, Spedali Civili di Brescia, University of Brescia, Brescia, Italy.
Abstract:
Current guidelines recommend concomitant surgical ablation (SA) of atrial fibrillation (AF) in the context of mitral valve disease. A variety of energy sources have been tested for SA to perform effective transmural lesions reliably. To date, only radiofrequency and cryothermy energies are considered viable options. The gold standard for SA is the Cox-Maze ablation set, especially for non-paroxysmal AF (nPAF), with the aim of interrupting macro-reentrant drivers perpetuating AF, without hampering the sinus node activation of both atria, and to maintain the atrioventricular synchrony. Although the efficacy of SA in terms of early and late sinus rhythm restoration has been clearly demonstrated over the years, concomitant AF ablation is still underperformed in patients with AF undergoing cardiac surgery. From a surgical standpoint, concerns have been raised about whether a single (left) or double atriotomy would be justified in AF patients undergoing a "non-atriotomy" surgical procedure, such as aortic valve or revascularization surgery. Thus, an array of simplified lesion sets have been described in the last decade, which have unavoidably hampered procedural efficacy, somewhat jeopardizing the standardization process of ablation surgery. As a matter of fact, the term "Maze" has improperly become a generic term for SA. Surgical interventions that do not align with the principles of forming conduction-blocking lesions according to the Maze pattern, cannot be classified as Maze procedures. In this complex scenario, a tailored approach according to the different AF patterns has been proposed: for patients with concomitant nPAF, a biatrial Cox-Maze ablation is recommended. Conversely, it might be reasonable to limit lesions to the left atrium or the pulmonary veins in patients with paroxysmal AF (PAF) in some clinical scenarios. The aim of this review is to provide an overview of the current ablation strategies for patients with AF undergoing concomitant cardiac surgery.
Insights
Surgical ablation for atrial fibrillation (AF) is recommended with mitral valve disease but underperformed. Tailored strategies, like Cox-Maze for non-paroxysmal AF, improve outcomes.
Area of Science:
- Cardiovascular Surgery
- Cardiac Electrophysiology
Background:
- Current guidelines advocate surgical ablation (SA) for atrial fibrillation (AF) during mitral valve surgery.
- Despite proven efficacy, SA is underutilized due to surgical concerns and a lack of standardization.
Purpose of the Study:
- To review current surgical ablation strategies for patients with AF undergoing cardiac surgery.
- To discuss the challenges and tailored approaches for effective AF ablation.
Main Methods:
- Review of current literature on surgical ablation techniques for AF.
- Analysis of energy sources, lesion sets, and procedural standardization.
Main Results:
- Radiofrequency and cryothermy are viable energy sources for SA.
- The Cox-Maze procedure is effective, especially for non-paroxysmal AF (nPAF).
- Simplified lesion sets may compromise efficacy; a tailored approach based on AF type is proposed.
Conclusions:
- Effective SA requires adherence to Maze principles; "Maze" is often misused for non-standard procedures.
- A biatrial Cox-Maze is recommended for nPAF.
- Left atrial or pulmonary vein isolation may suffice for paroxysmal AF (PAF) in select cases.

