Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Primary Lymphoid Organs01:16

Primary Lymphoid Organs

Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
Detailed Structure and Function of Lymph Nodes01:23

Detailed Structure and Function of Lymph Nodes

Lymph nodes are bean-shaped structures that cluster along the lymphatic vessels in the inguinal, axillary, and cervical regions. Each node is divided into compartments by a capsule that extends trabeculae inward.
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Residential tree canopy and allostatic load in US adults: a population-based cross-sectional study.

Lancet regional health. Americas·2026
Same author

Characterizing pseudoangiomatous stromal hyperplasia (PASH) of the breast.

Histopathology·2026
Same author

Technical error prevalence in the complete pathology tissue testing process: a systematic review and meta-analysis.

BMJ open quality·2026
Same author

The grossing competency evaluation process in a pathology residency program: transitioning from paper to digital.

American journal of clinical pathology·2026
Same author

The Association Between Preoperative Tamsulosin Use and Intraoperative Hypotension.

Journal of cardiothoracic and vascular anesthesia·2026
Same author

The association of contemporary mortgage lending bias and receipt of guideline-concordant systemic treatment among older women with breast cancer.

Breast cancer research and treatment·2025

Related Experiment Video

Updated: May 9, 2026

A Simple and Rapid Protocol to Non-enzymatically Dissociate Fresh Human Tissues for the Analysis of Infiltrating Lymphocytes
07:29

A Simple and Rapid Protocol to Non-enzymatically Dissociate Fresh Human Tissues for the Analysis of Infiltrating Lymphocytes

Published on: December 6, 2014

20.0K

Improving resource utilization: Axillary lymph node core biopsy triaging for lymphoma.

Carl Dernell1, John Astle1, Abraham Bogachkov2

  • 1Departments of Pathology, Medical College of Wisconsin, Milwaukee, WI, US.

American Journal of Clinical Pathology
|April 9, 2024
PubMed
Summary
This summary is machine-generated.

Hematopathology resources were overused for axillary lymph node core biopsies (AxLNCB) in breast cancer screening. A predictive tool using patient characteristics could optimize resource allocation for these biopsies.

Keywords:
axillaflow cytometrylymph nodeutilization

More Related Videos

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy
07:51

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy

Published on: June 1, 2019

19.4K
Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
05:52

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

11.4K

Related Experiment Videos

Last Updated: May 9, 2026

A Simple and Rapid Protocol to Non-enzymatically Dissociate Fresh Human Tissues for the Analysis of Infiltrating Lymphocytes
07:29

A Simple and Rapid Protocol to Non-enzymatically Dissociate Fresh Human Tissues for the Analysis of Infiltrating Lymphocytes

Published on: December 6, 2014

20.0K
The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy
07:51

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy

Published on: June 1, 2019

19.4K
Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
05:52

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

11.4K

Area of Science:

  • Pathology
  • Oncology
  • Diagnostic Imaging

Background:

  • Axillary lymph node core biopsies (AxLNCB) are crucial in breast cancer staging.
  • Hematopathology consultation is often sought for AxLNCB interpretation.
  • The necessity and extent of hematopathology involvement require evaluation.

Purpose of the Study:

  • To assess the utilization of hematopathology resources for AxLNCB specimens.
  • To identify factors influencing hematopathology consultation for AxLNCB.
  • To determine the actual prevalence of hematologic malignancies in AxLNCB.

Main Methods:

  • Retrospective review of 594 AxLNCB specimens over 30 months.
  • Analysis of hematopathology resource utilization (triage, review).
  • Chart review for patient demographics and radiographic features.

Main Results:

  • 61.6% of AxLNCB were benign, 38.6% malignant.
  • Only 9.3% of malignant cases had hematologic malignancy.
  • 94% of cases were triaged for lymphoma, 81% reviewed by hematopathologists.
  • Six factors predicted hematologic malignancy risk: male sex, bilateral lymphadenopathy, diffuse cortical thickening, lack of breast cancer, older age, and prior hematologic malignancy history.

Conclusions:

  • Significant overuse of hematopathology resources for AxLNCB was observed.
  • A predictive tool based on clinical parameters can optimize hematopathology consultation.
  • Improved resource allocation can enhance efficiency in evaluating AxLNCB.