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Updated: Jun 17, 2026

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
Published on: February 28, 2012
Longer and better lives for patients with atrial fibrillation: the 9th AFNET/EHRA consensus conference
Dominik Linz1,2, Jason G Andrade3,4, Elena Arbelo5,6,7,8
1Department of Cardiology, Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands.
Insights
Active rhythm management is recommended for atrial fibrillation (AF) patients. Lower arrhythmia burden in AF reduces stroke risk, but more research is needed for accurate prediction in these cases.
Area of Science:
- Cardiology
- Electrophysiology
- Digital Health
Background:
- Recent trials highlight benefits of active rhythm management in atrial fibrillation (AF).
- A low arrhythmia burden correlates with reduced AF-related complications.
- The 9th AFNET/EHRA Consensus Conference convened experts to discuss AF management.
Purpose of the Study:
- To summarize key outcomes from the 9th AFNET/EHRA Consensus Conference.
- To provide guidance on active rhythm management and stroke risk in AF patients.
- To highlight the role of comprehensive care and emerging technologies in AF treatment.
Main Methods:
- Consensus conference involving 83 international experts.
- Discussion and synthesis of recent trial data and clinical findings.
- Focus on device-detected AF, stroke risk prediction, and concomitant conditions.
Main Results:
- Active rhythm management should be a default treatment for suitable AF patients.
- Device-detected AF with low burden indicates low stroke risk; anticoagulation benefits and risks require careful consideration.
- Enhanced stroke risk prediction needs further research using biomarkers, genetics, and imaging.
- AF diagnosis necessitates systematic evaluation and treatment of co-existing cardiovascular conditions.
- Machine learning shows promise for AF detection and prediction, requiring clinical-data science collaboration.
Conclusions:
- Patients with lower AF burden face reduced risks of stroke and cardiovascular events.
- Integrated management combining rhythm control, anticoagulation, rate control, and treatment of comorbidities improves patient outcomes.
- Further research and technological integration are crucial for optimizing AF care.
Aims:
Recent trial data demonstrate beneficial effects of active rhythm management in patients with atrial fibrillation (AF) and support the concept that a low arrhythmia burden is associated with a low risk of AF-related complications. The aim of this document is to summarize the key outcomes of the 9th AFNET/EHRA Consensus Conference of the Atrial Fibrillation NETwork (AFNET) and the European Heart Rhythm Association (EHRA).
Methods And Results:
Eighty-three international experts met in Münster for 2 days in September 2023. Key findings are as follows: (i) Active rhythm management should be part of the default initial treatment for all suitable patients with AF. (ii) Patients with device-detected AF have a low burden of AF and a low risk of stroke. Anticoagulation prevents some strokes and also increases major but non-lethal bleeding. (iii) More research is needed to improve stroke risk prediction in patients with AF, especially in those with a low AF burden. Biomolecules, genetics, and imaging can support this. (iv) The presence of AF should trigger systematic workup and comprehensive treatment of concomitant cardiovascular conditions. (v) Machine learning algorithms have been used to improve detection or likely development of AF. Cooperation between clinicians and data scientists is needed to leverage the potential of data science applications for patients with AF.
Conclusions:
Patients with AF and a low arrhythmia burden have a lower risk of stroke and other cardiovascular events than those with a high arrhythmia burden. Combining active rhythm control, anticoagulation, rate control, and therapy of concomitant cardiovascular conditions can improve the lives of patients with AF.
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