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Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Evaluation of the Periodontal Inflammatory Effect on Erythrocyte Sedimentation Rate: A Clinical Study
Bipin K Yadav1, Rajesh K Thakur1, Sanjay K Kannaujia2
1Department of Periodontology, Faculty of Dental Sciences, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India.
Context:
The link between oral infections and systemic disease is a well-proven hypothesis in the current literature. This relationship is the result of interaction between periodontal microbe that triggers inflammatory processes leading to the secretion of cytokines and other mediators of inflammation resulting in the systemic effects of pathogenesis.
Materials And Methods:
In this study, erythrocyte sedimentation rate (ESR), probing pocket depth, plaque index, gingival index, and the parameters were assessed initially and 1 month after scaling and root planing (SRP).
Statistical Analysis Used:
The paired t-test and the Pearson correlation were needed to examine and compare measured data.
Results:
The data from the study reveal that all the clinical parameters like the plaque index, the gingival index, and the probing pocket depth were statistically significantly reduced after 1 month of SRP with respect to baseline. While ESR mean value was also reduced, that is, 3.27 ± 1.24 mm/hr which was also considered statistically significant.
Conclusions:
The findings from the study showed a positive correlation between periodontal inflammation and ESR.

