Lesion Sterilization Tissue Repair: A Review

Area of Science:

• Dentistry
• Endodontics
• Pediatric Dentistry

Background:

• Primary molars with extensive periapical pathosis and extreme resorption present complex treatment challenges.
• Current therapeutic options require careful consideration of regenerative and restorative approaches.

Purpose of the Study:

• To provide a comprehensive review of the components and application of lesion sterilization and tissue restoration (LSTR) in pediatric endodontics.
• To elucidate the role of a triple antibiotic mixture in LSTR for primary molars.

Main Methods:

• Literature review focusing on studies related to LSTR, periapical pathosis, and primary molar regeneration.
• Analysis of the composition and mechanism of action of antibiotic agents used in LSTR.

Main Results:

• Lesion sterilization and tissue restoration (LSTR) involves a multi-faceted approach to manage severe dental infections in primary teeth.
• A triple antibiotic mixture, when used in an appropriate medium, demonstrates efficacy in sterilizing lesions and promoting tissue healing.

Conclusions:

• LSTR offers a viable treatment strategy for primary molars with extensive periapical pathosis and resorption.
• The judicious use of a triple antibiotic mixture is a key component in successful LSTR outcomes, preserving the integrity of primary dentition.