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Auto-PAP Titration Efficacy in Obstructive Sleep Apnea: A Single-Center Experience
Sanjay D Gabhale1, Ekta Gupta2, Mahavir Satishchand Bagrecha3
1Department of Respiratory Medicine, Dr D. Y. Patil Medical College, Hospital and Research Centre, Dr D. Y. Patil Vidyapeeth, Pimpri, Pune, Maharashtra, India.
Journal of Pharmacy & Bioallied Sciences
|April 10, 2024
Summary
Auto positive airway pressure (PAP) titration is effective for treating obstructive sleep apnea (OSA). This study found auto-PAP titration to be a successful and potentially cost-effective alternative to traditional CPAP titration methods.
Area of Science:
- Sleep Medicine
- Respiratory Physiology
Background:
- Obstructive sleep apnea (OSA) is a serious sleep-related breathing disorder.
- Continuous positive airway pressure (CPAP) is a primary treatment for moderate to severe OSA.
- Auto/manual CPAP titration studies determine optimal treatment pressure.
Purpose of the Study:
- To evaluate the effectiveness of auto-PAP titration in patients with obstructive sleep apnea.
- To assess auto-PAP titration as a potential alternative to attended CPAP titration.
Main Methods:
- A prospective, cross-sectional clinical study was conducted at a tertiary care center.
- Subjects with moderate and severe OSA undergoing auto-PAP titration were included.
- Efficacy of auto-PAP titration was evaluated, along with demographic factors.
Main Results:
- Fifty percent of patients achieved optimal auto-PAP titration.
- Forty percent showed good titration, and ten percent showed suitable titration.
- No patients fell into the unacceptable titration group.
Conclusions:
- Auto-PAP titration demonstrated positive results in patients with moderate and severe OSA.
- Unattended auto-PAP titration is a successful technique.
- Auto-PAP titration may reduce labor and cost compared to attended CPAP titration.

