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Related Concept Videos

Teeth01:15

Teeth

404
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
404

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Author Spotlight: Establishing an Accurate Microhardness Testing Protocol for Craniofacial Tissues
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Published on: April 26, 2024

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Micro-CT study on isolated teeth with hereditary dentin defects.

Anpeng Han1, Fangli Lu2, Yuping Lu3

  • 1Dept. of Stomatology, the First Affiliated Hospital of Zhengzhou University, Henan Stomatological Hospital, Zhengzhou 450052, China.

Hua Xi Kou Qiang Yi Xue Za Zhi = Huaxi Kouqiang Yixue Zazhi = West China Journal of Stomatology
|April 10, 2024
PubMed
Summary
This summary is machine-generated.

Micro-computed tomography (Micro-CT) revealed significant differences in tooth structure and mineralization density between dentinogenesis imperfecta type II (DGI-II) and dentin dysplasia type I (DD-I) patients compared to healthy individuals. DD-I teeth showed more severe mineralization defects than DGI-II teeth.

Keywords:
Micro-CTdentin dysplasiadentinogenesis imperfectathree-dimensional reconstructiontooth mineralization

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Area of Science:

  • Dental science
  • Biomaterials science
  • Radiology

Background:

  • Dentinogenesis imperfecta type II (DGI-II) and dentin dysplasia type I (DD-I) are hereditary dentin defects affecting tooth structure and mineralization.
  • Understanding the three-dimensional (3D) internal structures and mineralization densities of these teeth is crucial for diagnosis and management.

Purpose of the Study:

  • To construct 3D structures of teeth from patients with DGI-II and DD-I using Micro-CT.
  • To analyze the internal morphology and hard tissue mineralization density of affected teeth.

Main Methods:

  • Reconstruction of 3D tooth structures from third molars of DGI-II, DD-I patients, and healthy controls using Micro-CT.
  • Observation of internal structures along sagittal and transverse planes.
  • Calculation of grayscale values in enamel, crown dentin, and root dentin to assess mineralization density.

Main Results:

  • Successful 3D reconstruction of teeth with hereditary dentin defects, including enamel cap, dentin core, and pulp cavity.
  • DGI-II teeth exhibited incompletely calcified pulp cavities and narrow root canals.
  • DD-I teeth showed obliterated pulp cavities and root canals, with absent roots; both DGI-II and DD-I groups had lower mineralization than controls, with DD-I showing more significant root dentin mineralization reduction.

Conclusions:

  • Micro-CT is an effective method for 3D reconstruction and quantitative analysis of mineralization density in teeth with hereditary dentin defects.
  • Both DGI-II and DD-I teeth display reduced dentin mineralization, with DD-I being more severely affected.
  • Abnormal pulp cavity calcification and narrow or occluded root canals are characteristic findings.