Related Experiment Video
Updated: Jun 28, 2025
04:19
A Computer-Based Platform for Aiding Clinicians in Eating Disorder Analysis and Diagnosis
Published on: May 10, 2022
3.8K
Association Between Type 1 Diabetes Mellitus and Eating Disorders: A Systematic Review and Meta-Analysis
Yomna E Dean1, Karam R Motawea1, Muaaz Aslam2
1Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Endocrinology, Diabetes & Metabolism
|April 10, 2024
Summary
Individuals with type 1 diabetes mellitus (T1DM) have a significantly higher risk of eating disorders (EDs), especially bulimia nervosa and binge eating. Female diabetics are also at greater risk for insulin omission or misuse.
Area of Science:
- Endocrinology
- Psychiatry
- Metabolic Disorders
Background:
- Previous meta-analyses yielded inconclusive results on the association between eating disorders (EDs) and type 1 diabetes mellitus (T1DM).
- This study aimed to analyze specific EDs and disordered eating behaviors prevalent in T1DM patients.
Approach:
- Conducted a comprehensive literature search across PubMed, Scopus, and Web of Science databases.
- Included only observational controlled studies published before January 17, 2023.
- Utilized Revman software (version 5.4) for meta-analysis.
Key Points:
- T1DM patients exhibit a 2.47-fold increased risk of EDs compared to non-diabetic individuals.
- Bulimia nervosa (2.80-fold risk) and binge eating (1.53-fold risk) are particularly associated with T1DM.
- The elevated risk of EDs in T1DM persists regardless of diagnostic questionnaire type (DM-validated or generic).
- Insulin omission/misuse prevalence was 10.3%, with females showing a significantly higher risk than males.
Conclusions:
- A significant link exists between T1DM and EDs, notably bulimia and binge eating.
- Female individuals with T1DM face a higher risk of insulin misuse/omission.
- Recommends early, proactive screening and tailored interventions combining diabetes and ED management, with psychiatric referral.
Related Concept Videos
01:22Diabetes Mellitus: Overview and Type I Subtype
2.6K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.6K
01:20Pathophysiology of Diabetes
924
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
924
01:22Diabetes Mellitus: Type 2 and Gestational
2.3K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.3K
01:15Diabetes: Symptoms, Diagnosis, and Complications
528
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
528
01:19Psychoneuroimmunology: Diabetes and Cancer
28
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
28
01:36Carbohydrate Metabolism
11.1K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
11.1K