[Current concepts concerning the genesis of vestibulo-vegetative disorders in weightlessness]

The up-to-date hypotheses of the genesis of vestibulo-vegetative disorders in weightlessness are taken under critical analysis. Preference is given to the concept which attaches greatest importance to the changes in stereotyped interactions of analyzers responsible for space perception. It is, however, emphasized that neither hypothesis can account for all the phenomena seen in crewmembers in orbital flight. It is, therefore, indicated that mechanisms of vestibulo-vegetative disorders need further study. It is believed that the most promising line of research is to study the role of endogenous factors determining individual variations of motion sickness susceptibility.