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Mutualism is a symbiotic interaction in which all participating organisms benefit. These relationships can be obligate or facultative and are fundamental to ecosystem functions across diverse biological systems.Plant–Fungi MutualismOne well-known example is the association between plant roots and mycorrhizal fungi, such as Rhizophagus species. The fungal hyphae penetrate the root hairs and the epidermis, forming an extensive hyphal network that establishes a symbiotic association. Through this...
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Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
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Nanosafety: a Perspective on Nano-Bio Interactions.

Bengt Fadeel1, Arturo A Keller2

  • 1Institute of Environmental Medicine, Karolinska Institutet, 17177, Stockholm, Sweden.

Small (Weinheim an Der Bergstrasse, Germany)
|April 10, 2024
PubMed
Summary

Engineered nanomaterials offer benefits but require careful study of health and environmental impacts. Researchers suggest treating nanomaterials as biological entities for better regulation and understanding.

Keywords:
bio‐coronaeco‐coronananomaterialsnanosafetysafe‐by‐design

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Area of Science:

  • Nanotechnology
  • Environmental Science
  • Toxicology

Background:

  • Engineered nanomaterials offer societal benefits in environmental remediation, biomedical applications, and energy.
  • Increasing sophistication of nanomaterials necessitates scrutiny of potential human health and environmental risks.

Purpose of the Study:

  • To provide a critical perspective on current nanotoxicological research.
  • To advocate for leveraging knowledge of biological interactions for a comprehensive impact assessment.
  • To propose regulating nanomaterials as biological entities.

Main Methods:

  • Critical review of existing nanotoxicological research.
  • Analysis of biological interactions of nanomaterials.
  • Conceptual framework for nanomaterial regulation.

Main Results:

  • Current nanotoxicological research needs enhancement by focusing on biological interactions.
  • Understanding nanomaterial behavior requires viewing them as analogous to biological entities.
  • A new regulatory approach is proposed based on this analogy.

Conclusions:

  • It is crucial to integrate knowledge of biological interactions into nanotoxicology.
  • Viewing nanomaterials as biological entities can lead to a more accurate impact assessment.
  • Regulation of nanomaterials should consider their biological-like properties.