Related Experiment Video
Updated: Jun 28, 2025

Echocardiographic Assessment Using Subxiphoid-Only Examination for Hypotensive Patients
Published on: April 18, 2025
Reported Physical Symptoms During Screening Echocardiography Are Not Associated With Presence of Suspected
Mohammad Reza Movahed1, Ashkan Bahrami2, Sharon Bates3
1From the Department of Medicine, University of Arizona Sarver Heart Center, Tucson, AZ.
Sudden cardiac death can be the first sign of hypertrophic cardiomyopathy (HCM). This study found no association between physical symptoms and suspected HCM in 4120 screened individuals.
Area of Science:
- Cardiology
- Genetics
- Preventive Medicine
Background:
- Hypertrophic cardiomyopathy (HCM) can be asymptomatic, with sudden death as its initial presentation.
- Early detection of HCM is crucial for preventing sudden cardiac events.
Purpose of the Study:
- To investigate the association between physical symptoms and the presence of suspected HCM.
- To determine if common symptoms correlate with HCM diagnosis in a screening population.
Main Methods:
- Echocardiographic screening was conducted on 4120 individuals aged 4-79.
- Suspected HCM was defined as left ventricular wall thickness ≥15 mm.
- Symptom prevalence was compared between participants with and without suspected HCM.
Main Results:
- The prevalence of suspected HCM was 1.1% in the study cohort.
- No significant association was found between physical symptoms (chest pain, palpitations, shortness of breath, lightheadedness, ankle swelling, dizziness) and suspected HCM.
- Symptom rates in HCM participants were comparable to the control group.
Conclusions:
- Screening echocardiography revealed no higher prevalence of physical symptoms in individuals with suspected HCM.
- Physical symptoms alone are not reliable indicators for identifying HCM in a screening setting.
Related Concept Videos
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
Cardiovascular System Abnormal Findings I: Inspection and Palpation
Abnormal findings observed during an inspection
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
Cardiovascular System Abnormal Findings II: Auscultation
Abnormal Heart Sounds
Gallops:
Exercise Stress Test
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes

