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Updated: Jun 28, 2025

4D Printed Bifurcated Stents with Kirigami-Inspired Structures
Published on: July 25, 2019
3D printing technology and its revolutionary role in stent implementation in cardiovascular disease
Muhammad Amir Khan1, Niyamat Khan1, Muneeb Ullah2
1Department of Foreign Medical Education, Fergana Medical Institute of Public Health, 2A Yangi Turon Street, Fergana 150100, Uzbekistan.
Insights
Cardiovascular disease (CVD) necessitates advanced treatments like vascular stents. Three-dimensional (3D) printing offers enhanced polymeric bioresorbable stents, improving mechanical performance and paving the way for precision medicine in cardiology.
Area of Science:
- Biomedical Engineering
- Cardiovascular Medicine
- Materials Science
Background:
- Cardiovascular disease (CVD), including coronary artery disease (CAD), is a major global health issue with complex risk factors.
- Current treatments like percutaneous coronary intervention and vascular stents aim to manage CVD but face challenges in optimizing stent performance.
- Minimizing restenosis, thrombosis, and neointimal hyperplasia while ensuring mechanical support are key goals for effective stent design.
Purpose of the Study:
- To review current stent technologies for cardiovascular disease (CVD).
- To explore the application of additive manufacturing (3D printing) in enhancing polymeric bioresorbable stents.
- To discuss the benefits, complications, and future potential of 3D-printed stents in precision cardiology.
Main Methods:
- Review of existing literature on cardiovascular stents and additive manufacturing (3D printing) techniques.
- Analysis of the mechanical properties and performance of polymeric bioresorbable stents.
- Examination of the integration of 3D printing in medical applications, particularly for cardiovascular implants.
Main Results:
- Additive manufacturing (3D printing) shows promise for improving the mechanical performance of bioresorbable stents.
- 3D printing enables customization of medical implants, supporting precision medicine and personalized treatment approaches.
- Patient-specific 3D-printed anatomical models are becoming crucial in medical procedures.
Conclusions:
- 3D printing technology offers a novel approach to developing advanced vascular stents with improved characteristics.
- This technology has the potential to reduce complications and enhance patient outcomes in cardiovascular interventions.
- 3D-printed solutions are poised to foster a new era of precision medicine in cardiology.
Abstract:
Cardiovascular disease (CVD), exemplified by coronary artery disease (CAD), is a global health concern, escalating in prevalence and burden. The etiology of CAD is intricate, involving different risk factors. CVD remains a significant cause of mortality, driving the need for innovative interventions like percutaneous coronary intervention and vascular stents. These stents aim to minimize restenosis, thrombosis, and neointimal hyperplasia while providing mechanical support. Notably, the challenges of achieving ideal stent characteristics persist. An emerging avenue to address this involves enhancing the mechanical performance of polymeric bioresorbable stents using additive manufacturing techniques And Three-dimensional (3D) printing, encompassing various manufacturing technologies, has transcended its initial concept to become a tangible reality in the medical field. The technology's evolution presents a significant opportunity for pharmaceutical and medical industries, enabling the creation of targeted drugs and swift production of medical implants. It revolutionizes medical procedures, transforming the strategies of doctors and surgeons. Patient-specific 3D-printed anatomical models are now pivotal in precision medicine and personalized treatment approaches. Despite its ongoing development, additive manufacturing in healthcare is already integrated into various medical applications, offering substantial benefits to a sector under pressure for performance and cost reduction. In this review primarily emphasizes stent technology, different types of stents, highlighting its application with some potential complications. Here we also address their benefits, potential issues, effectiveness, indications, and contraindications. In future it can potentially reduce complications and help in improving patients' outcomes. 3DP technology offers the promise to customize solutions for complex CVD conditions and help or fostering a new era of precision medicine in cardiology.
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