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Lethal mycotic pseudoaneurysm presenting as isolated sixth nerve palsy
Rasna Bhanuman1, Shriram Varadharajan2, Karthik Kumar1
1Neuro-Ophthalmology Department, Aravind Eye Hospital and Post Graduate Institute of Ophthalmology, Coimbatore, Tamil Nadu, India.
Abstract:
Pseudoaneurysm of the internal carotid artery caused by skull base osteomyelitis (SBO) is a lethal condition seen in immunocompromised patients, predominantly those with diabetes mellitus. Cranial nerve involvement is a common complication and generally indicates a poor prognosis. We report the case of a 62-year-old diabetic patient who presented with isolated sixth cranial nerve palsy. She had uncontrolled blood sugar levels and high erythrocyte sedimentation rate, and she suffered from pyelonephritis. Neuroimaging detected SBO with multiple secondary mycotic pseudoaneurysms prominent at the petrocavernous junction. Ischemia is the most common etiology for an isolated abducens nerve palsy, but in certain cases neuroimaging is warranted to prevent life-threatening complications. This case highlights the importance and urgency of identifying and managing such conditions.
Insights
Skull base osteomyelitis (SBO) can cause internal carotid artery pseudoaneurysms in diabetic patients, leading to cranial nerve palsy. Early diagnosis and management are crucial for preventing severe complications.
Area of Science:
- Neurology
- Infectious Diseases
- Vascular Surgery
Background:
- Skull base osteomyelitis (SBO) is a rare but serious infection.
- Internal carotid artery pseudoaneurysms are life-threatening complications of SBO, particularly in immunocompromised individuals like those with diabetes mellitus.
- Cranial nerve involvement, especially the abducens nerve (sixth cranial nerve), is a frequent complication associated with poor prognosis.
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