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Immune control in Kawasaki disease knowledge mapping: a bibliometric analysis
Lu Zhang1, Lifeng Shi1, Ruijie Zhang1
1Department of Neonatology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Insights
This bibliometric analysis maps immune control research in Kawasaki disease, identifying key institutions, countries, and journals. It highlights emerging trends like COVID-19
Area of Science:
- Pediatric Immunology
- Vascular Biology
- Bibliometric Analysis
Background:
- Kawasaki disease is a systemic vascular illness with unknown causes, primarily affecting young children.
- Research into immune system regulation in Kawasaki disease is a growing area of scientific interest.
- Understanding immune control mechanisms is crucial for managing this pediatric condition.
Purpose of the Study:
- To conduct a bibliometric analysis of research on immune control in Kawasaki disease.
- To identify current trends and future research directions in this field.
- To provide a comprehensive overview for researchers studying Kawasaki disease immunology.
Main Methods:
- Searched Web of Science Core Collection using keywords: "Kawasaki disease," "Kawasaki syndrome," and "immune control."
- Employed bibliometric analysis tools including VOSviewers, CiteSpace, and the R package "bibliometrix."
- Analyzed publication data to identify influential institutions, countries, journals, and research themes.
Main Results:
- A total of 294 studies were identified.
- Top contributing institutions include Chang Gung University and University of California San Diego.
- China, USA, and Japan lead in publications; Clinical and Experimental Immunology is a key journal.
- Recent keywords indicate a focus on COVID-19, SARS-CoV-2, and multisystem inflammatory syndrome in children.
Conclusions:
- This is the first bibliometric analysis to comprehensively map research on immune control in Kawasaki disease.
- The study identifies key research frontiers and emerging hot topics.
- Findings facilitate easier navigation for researchers investigating Kawasaki disease immune control.
Background:
Kawasaki disease is a systemic vascular disease with an unclear pathophysiology that primarily affects children under the age of five. Research on immune control in Kawasaki disease has been gaining attention. This study aims to apply a bibliometric analysis to examine the present and future directions of immune control in Kawasaki disease.
Methods:
By utilizing the themes "Kawasaki disease," "Kawasaki syndrome," and "immune control," the Web of Science Core Collection database was searched for publications on immune control in Kawasaki disease. This bibliometric analysis was carried out using VOSviewers, CiteSpace, and the R package "bibliometrix."
Results:
In total, 294 studies on immune control in Kawasaki disease were published in Web of Science Core Collection. The three most significant institutions were Chang Gung University, the University of California San Diego, and Kaohsiung Chang Gung Memorial Hospital. China, the United States, and Japan were the three most important countries. In this research field, Clinical and Experimental Immunology was the top-referred journal, while the New England Journal of Medicine was the most co-cited journal. The Web of Science Core Collection document by McCrindle BW et al. published in 2017 was the most cited reference. Additionally, the author keywords concentrated on "COVID-19," "SARS-CoV-2," and "multisystem inflammatory syndrome in children" in recent years.
Conclusion:
The research trends and advancements in immune control in Kawasaki disease are thoroughly summarised in this bibliometric analysis, which is the first to do so. The data indicate recent research frontiers and hot directions, making it easier for researchers to study the immune control of Kawasaki disease.
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