Related Experiment Video
Updated: Jun 28, 2025

26:48
Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis
Published on: July 4, 2007
18.0K
Immune control in Kawasaki disease knowledge mapping: a bibliometric analysis
Lu Zhang1, Lifeng Shi1, Ruijie Zhang1
1Department of Neonatology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Cardiology in the Young
|April 11, 2024
Summary
This bibliometric analysis maps immune control research in Kawasaki disease, identifying key institutions, countries, and journals. It highlights emerging trends like COVID-19
Area of Science:
- Pediatric Immunology
- Vascular Biology
- Bibliometric Analysis
Background:
- Kawasaki disease is a systemic vascular illness with unknown causes, primarily affecting young children.
- Research into immune system regulation in Kawasaki disease is a growing area of scientific interest.
- Understanding immune control mechanisms is crucial for managing this pediatric condition.
Purpose of the Study:
- To conduct a bibliometric analysis of research on immune control in Kawasaki disease.
- To identify current trends and future research directions in this field.
- To provide a comprehensive overview for researchers studying Kawasaki disease immunology.
Main Methods:
- Searched Web of Science Core Collection using keywords: "Kawasaki disease," "Kawasaki syndrome," and "immune control."
- Employed bibliometric analysis tools including VOSviewers, CiteSpace, and the R package "bibliometrix."
- Analyzed publication data to identify influential institutions, countries, journals, and research themes.
Main Results:
- A total of 294 studies were identified.
- Top contributing institutions include Chang Gung University and University of California San Diego.
- China, USA, and Japan lead in publications; Clinical and Experimental Immunology is a key journal.
- Recent keywords indicate a focus on COVID-19, SARS-CoV-2, and multisystem inflammatory syndrome in children.
Conclusions:
- This is the first bibliometric analysis to comprehensively map research on immune control in Kawasaki disease.
- The study identifies key research frontiers and emerging hot topics.
- Findings facilitate easier navigation for researchers investigating Kawasaki disease immune control.
Related Concept Videos
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
126
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
126
The JAK-STAT Signaling Pathway
8.8K
Several cytokine receptors have tightly bound Janus kinase or JAK proteins attached at their cytosolic tail. Small signaling molecules such as cytokines, growth hormones, or prolactins bind to the cytokine receptors and initiate their dimerization. The dimerization brings the cytosolic JAKs together that trans-phosphorylate and activates each other. The activated JAKs now phosphorylate cytosolic tails of the cytokine receptors, which serve as binding sites for adaptor proteins such as SH2...
8.8K
MAPK Signaling Cascades
5.5K
Mitogen-activated protein kinase, or MAPK pathway, activates three sequential kinases to regulate cellular responses such as proliferation, differentiation, survival, and apoptosis. The canonical MAPK pathway starts with a mitogen or growth factor binding to an RTK. The activated RTKs stimulate Ras, which recruits Raf or MAP3 Kinase (MAPKKK), the first kinase of the MAPK signaling cascade. Raf further phosphorylates and activates MEK or MAP2 Kinases (MAPKK), which in turn phosphorylates MAP...
5.5K

