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Updated: Jun 28, 2025

Sequencing Small Non-coding RNA from Formalin-fixed Tissues and Serum-derived Exosomes from Castration-resistant Prostate Cancer Patients
Published on: November 19, 2019
[Research progress of SOX9 in the evolution of prostate cancer]
Jing-Ting Dong1, Shao-San Kang1, Feng-Hong Cao1
1Department of Urology, Affiliated Hospital of North China University of Science and Technology, Tangshan, Hebei 063000,China .
Abstract:
Sex-determining region Y-box transcription factor 9(SOX9)is essential for prostate development. The dysregulation of SOX9 not only affects the occurrence of Prostate cancer (PCa), but also plays a key role in castration-resistant prostate cancer (CRPC). However, the mechanism of SOX9 affecting the evolution of PCa is still unclear. This paper mainly reviews the molecular mechanism and signal pathway related to the occurrence and development of SOX9 and PCa. SOX9 gene may be an important new biomarker in the development of PCa,providing new ideas for clinical diagnosis and treatment.
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