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Updated: Jun 28, 2025

An R-Based Landscape Validation of a Competing Risk Model
Published on: September 16, 2022
A brief step-by-step guide on conducting a systematic review and meta-analysis of prognostic model studies
Daniel G Rayner1, Ben Kim2, Farid Foroutan3
1Faculty of Health Sciences, Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
Abstract:
Prognostic models provide an avenue to predict the risk of individual patients and support shared-decision making. Many prognostic models are published annually, and systematic reviews provide an avenue to collate the existing evidence behind prognostic models to determine whether a model demonstrates adequate predictive performance and is ready for real-world use. This article provides a brief step-by-step guide on how to conduct a systematic review and meta-analysis of prognostic model studies and how these reviews differ from systematic reviews of therapy and diagnosis.
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