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Related Concept Videos

Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

179
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
179
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

242
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
242
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

228
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
228
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

325
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
325
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

142
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
142

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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
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Review canine tuberculosis - An emerging concern.

Emi N Barker1, Conor O'Halloran2, Danièlle A Gunn-Moore2

  • 1Langford Vets, University of Bristol, Langford BS40 5DU, United Kingdom; Bristol Veterinary School, University of Bristol, Langford BS40 5DU, United Kingdom.

Veterinary Journal (London, England : 1997)
|April 11, 2024
PubMed
Summary

Canine tuberculosis, caused by Mycobacterium tuberculosis-complex organisms, is an emerging concern. New diagnostic tests and optimized antimicrobial treatments offer improved outcomes for affected dogs.

Keywords:
Interferon-gamma release assayMycobacterium bovisTreatmentTuberculosis Zoonosis

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Area of Science:

  • Veterinary Medicine
  • Infectious Diseases
  • Microbiology

Background:

  • Canine mycobacterial disease, recognized over a century ago, is increasingly prevalent.
  • Tuberculosis in dogs is exclusively caused by Mycobacterium tuberculosis-complex (MTBC) organisms: M. tuberculosis, M. bovis, and M. microti.

Purpose of the Study:

  • To review the clinical presentation, diagnosis, treatment, and prognosis of canine tuberculosis.
  • To highlight emerging diagnostic and therapeutic strategies for canine mycobacterial infections.

Main Methods:

  • Review of existing literature on canine tuberculosis.
  • Discussion of diagnostic modalities including culture, PCR, and interferon-gamma release assays.
  • Analysis of antimicrobial treatment protocols.

Main Results:

  • Molecular diagnostics like PCR and interferon-gamma release assays provide alternatives to traditional culture methods, which have limitations in availability, sensitivity, and turnaround time.
  • Optimized triple antimicrobial protocols demonstrate a high success rate in treated canine cases.

Conclusions:

  • Canine tuberculosis requires updated diagnostic and treatment approaches due to its emerging status.
  • Prompt diagnosis and effective antimicrobial therapy are crucial for successful management of canine mycobacterial disease.