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Complement-mediated thrombotic microangiopathy on a background of Alport syndrome: A case report
Craig Peter Coorey1,2, Theo de Malmanche3,4, Angela Chou5
1Renal Unit, Gosford Hospital, Gosford, New South Wales, Australia.
Nephrology (Carlton, Vic.)
|April 11, 2024
Abstract:
Here we present a case of complement-mediated thrombotic microangiopathy (TMA) in a patient who has a background of Stage 5 chronic kidney disease secondary to Alport syndrome. We explain our approach to the diagnosis of TMA, especially the reliance on non-renal manifestations of TMA and the role of kidney biopsy given there was a background of advanced kidney impairment at baseline.

