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3D and 4D assembly of functional structures using shape-morphing materials for biological applications
Soheyl Mirzababaei1, Lily Alyssa Kera Towery1, Molly Kozminsky1,2
1Department of Chemical and Biological Engineering, Iowa State University, Ames, IA, United States.
Frontiers in Bioengineering and Biotechnology
|April 12, 2024
Summary
Shape-morphing materials transform 2D into 3D structures using principles like origami. These advanced materials enable the creation of functional 3D biomimetic designs for diverse biomedical applications.
Area of Science:
- Biomaterials Science
- Materials Engineering
- Biofabrication
Background:
- 3D structures are vital for biological functions, increasing demand for in vitro fabrication.
- Shape-morphing materials offer precise control over 3D material properties for specific applications.
Purpose of the Study:
- To review manufacturing techniques for 3D shape-morphing structures.
- To discuss common architectures and biomedical applications of these materials.
Main Methods:
- Summarizing fabrication techniques like lithography and 3D printing.
- Analyzing origami and kirigami principles for 2D to 3D transformation.
- Highlighting stimulus-responsive materials for dynamic architecture changes.
Main Results:
- Developed architectures include gripping, rolling, and folding structures.
- Biomedical applications span sensors, scaffolds, and minimally invasive medical devices.
- Shape-morphing materials enable dynamic architectural changes, acting as a 'fourth dimension' in manufacturing.
Conclusions:
- Shape-morphing materials offer significant potential for creating complex, functional 3D structures.
- Future directions involve biomimetic and bioinspired designs for advanced biomedical solutions.
- Challenges remain in optimizing these materials for sophisticated in vivo applications.
