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Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview

Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview

In inductively coupled plasma–mass spectrometry (ICP–MS), an inductively coupled plasma (ICP) torch is used as an atomizer and ionizer. Solid samples are dissolved and volatilized before being introduced into the high-temperature argon plasma, while solution samples are nebulized and passed through the high-temperature argon plasma. Plasma dissociates the analytes and ionizes their component atoms to form a mixture of positive ions and molecular species. The positive ions are then...

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ICP-MS-Based Characterization and Quantification of Nano- and Microstructures.

Antonio R Montoro Bustos¹

¹The Material Measurement Laboratory, Chemical Sciences Division, National Institute of Standards and Technology (NIST), Gaithersburg, MD 20899, USA.

Nanomaterials (Basel, Switzerland)

|April 12, 2024

Summary

Inductively coupled plasma mass spectrometry (ICP-MS) offers powerful multi-elemental analysis at ultratrace levels. This versatile technique has significantly advanced scientific research since the 1980s.

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Area of Science:

Analytical Chemistry
Atomic Spectroscopy
Mass Spectrometry

Background:

Inductively coupled plasma mass spectrometry (ICP-MS) emerged in the 1980s.
ICP-MS is a leading technique for multi-elemental and multi-isotopic analysis.
It enables ultratrace detection of metals, metalloids, and non-metals.

Discussion:

The evolution of ICP-MS has cemented its role in scientific research.
Its versatility allows for diverse applications across various scientific disciplines.
ICP-MS provides unparalleled sensitivity for trace element quantification.

Key Insights:

ICP-MS is a cornerstone for ultratrace elemental and isotopic analysis.
The technique's power lies in its multi-elemental capabilities.
Significant advancements have been made since its commercial introduction.

Outlook:

Continued development of ICP-MS promises enhanced analytical performance.
Future applications will likely expand into new research frontiers.
ICP-MS remains critical for environmental, clinical, and materials science research.