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Updated: Jun 28, 2025
Platelet-Derived Extracellular Vesicle Functionalization of Ti Implants
Published on: August 5, 2021
A Prospective Report of the Clinical Outcome of TiUnite Implants at 20 Years of Follow-up
Purpose:
To present a survival analysis of 133 consecutively placed moderately rough implants, all with a total follow-up of 20 years.
Materials And Methods:
A total of 133 implants of the same brand placed in 46 patients at the same county clinic in Sweden were followed up prospectively over 20 years and analyzed for survival and bone height, the latter evaluated in periapical radiographs.
Results:
A total of 7 implants failed, 4 of which were in the same patient. Implant failure was associated with a combination of smoking and bruxism in 5 of the 7 failed cases. A 20-year survival rate of 94.7% was observed. Average marginal bone loss (MBL) at 20 years of follow-up was 0.543 ± 1.193 mm, with 9 implants having more than 2 mm of MBL. A total of 20 patients with 25 implants dropped out of the study; however, if death of the patient is excluded as a dropout reason, only 3 implants in 3 patients were unaccounted for.
Conclusions:
Good clinical results in the 95% survival range were observed with moderately rough implants over a 20-year follow-up period.
