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Related Concept Videos

Clinical Trials01:16

Clinical Trials

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Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
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Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

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The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
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Pulse rhythm01:30

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Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
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Data Collection I01:30

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Data collection gathers information needed to make accurate judgments about a patient's present condition. During a health history interview, subjective data is collected from the patient, their caregivers, or family members, and objective data is collected through observations and physical assessment. Patients are the primary source of subjective data. Thus information gathered from patients through interviews, observations, and physical examination is primary data. Secondary sources of...
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Updated: Jun 28, 2025

Author Spotlight: Automated Deep Brain Stimulation for Parkinson's Disease - Exploring the Possibilities and Challenges of Home Monitoring
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Remote Monitoring and Data Collection for Decentralized Clinical Trials.

Bobby Daly1, Otis W Brawley2, Mary K Gospodarowicz3

  • 1Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine, New York, New York.

JAMA Network Open
|April 12, 2024
PubMed
Summary
This summary is machine-generated.

Decentralized clinical trial technologies show low adoption in oncology, but industry anticipates significant growth. Future adoption of digital recruitment and local networks can enhance patient centricity.

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Area of Science:

  • Clinical trial operations
  • Pharmaceutical industry
  • Patient centricity

Background:

  • Low patient enrollment in cancer clinical trials is partly due to financial and logistical burdens, disproportionately affecting underserved populations.
  • The COVID-19 pandemic accelerated the adoption of decentralized clinical trial (DCT) operations by pharmaceutical companies.

Purpose of the Study:

  • To assess the global adoption of DCT technologies.
  • To identify factors influencing DCT adoption.
  • To understand industry aspirations for more patient-centric trials.

Main Methods:

  • A survey was administered to global biopharmaceutical companies within the Bloomberg New Economy International Cancer Coalition.
  • The survey focused on registrational clinical trials and collected data from October 1 to December 31, 2022.
  • Data analysis included descriptive statistics to evaluate technology adoption, patient centricity outcomes, and barriers/facilitators.

Main Results:

  • All 8 invited companies responded, representing 33% of the oncology market.
  • DCT adoption in oncology trials generally lags behind other therapeutic areas.
  • Electronic diaries and electronic clinical outcome assessments show the highest current adoption rates (around 50%), while local physician networks have the lowest (around 7%).

Conclusions:

  • Industry anticipates substantial increases in DCT adoption over the next 5 years, with an expected 40% rise in 8 out of 11 surveyed technologies for oncology.
  • Digital recruitment, local imaging, and local physician networks are identified as key technologies for improving patient centricity.
  • Increased adoption of DCT technologies can foster more accessible, less burdensome, and inclusive clinical trials.