Cohort profile: the European Unified Registries On Heart Care Evaluation and Randomized Trials (EuroHeart)-acute...

Area of Science:

• Cardiology
• Public Health
• Health Services Research

Background:

• The European Unified Registries On Heart Care Evaluation and Randomized Trials (EuroHeart) initiative aims to enhance cardiovascular disease patient care.
• A collaboration of acute coronary syndrome/percutaneous coronary intervention (ACS/PCI) registries is established in seven European Society of Cardiology member countries.

Purpose of the Study:

• To improve the quality of care and clinical outcomes for patients with cardiovascular disease.
• To establish a collaborative framework for ACS/PCI registries across multiple European countries.

Main Methods:

• Individual patient-level data for ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI) were collected.
• Data encompassed demographics, clinical characteristics, in-hospital care, outcomes, and discharge medications, aligned with EuroHeart standards.
• Aggregated data from 192 hospitals across seven countries (Estonia, Hungary, Iceland, Portugal, Romania, Singapore, Sweden) were analyzed for the period January 1, 2022, to December 31, 2022.

Main Results:

• A total of 40,021 admissions were recorded (STEMI 46.7%, NSTEMI 53.3%).
• The mean age of the cohort was 67.9 years (SD 12.6), with 31.6% women.
• Data included up to 155 variables per patient, facilitating detailed analysis.

Conclusions:

• The EuroHeart ACS/PCI registry collaboration prospectively collects and analyzes individual patient data nationally.
• Aggregated results are transferred to the EuroHeart Data Science Centre for international reporting and insights.
• The platform will expand to include more countries, offering continuous insights for quality improvement, research, and clinical trials.