[Ultrastructure of blast cells in patients with myeloblastic, monoblastic and myelomonoblastic leukemia]

Electron microscopy was applied to study and compare blast cells in 7 patients with acute myeloblastic, 4 with acute monoblastic and 11 patients with acute myelomonoblastic leukemias. Three morphological types of blast cells are described for acute myeloblastic leukemia and 2 types of blast cells for acute monoblastic leukemia. In acute myelomonoblastic leukemia, no specific cells characteristic but for this disease pattern were detected while the main tumor substrate included the different types of blast cells described for acute myeloblastic and monoblastic leukemias. A patients also manifests the predominance of the same type of blast cells, with no combination of different types. Ultrastructure of blast cells in acute non-lymphoblastic leukemias and therapeutic approaches are discussed.