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Related Concept Videos

Muscle Stimulation Frequency01:22

Muscle Stimulation Frequency

The contraction strength of muscles is regulated by motor neurons, which modulate the frequency of action potentials dispatched to the motor units based on the body's requirements. This process of varying the muscle stimulation frequency allows muscles to contract with a force that is precisely tailored to the needs of the moment, whether lifting a feather or a heavy box.
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...

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Related Experiment Video

Updated: May 8, 2026

Treating Low Back Pain in Failed Back Surgery Patients with Multicolumn-lead Spinal Cord Stimulation
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Healthcare Utilization (HCU) Reduction with High-Frequency (10 kHz) Spinal Cord Stimulation (SCS) Therapy.

Vinicius Tieppo Francio1,2, Logan Leavitt2, John Alm2

  • 1Department of Anesthesiology and Pain Medicine, The University of Kansas Medical Center, Kansas City, KS 66160, USA.

Healthcare (Basel, Switzerland)
|April 13, 2024
PubMed
Summary

High-frequency spinal cord stimulation (SCS) significantly reduces healthcare utilization, including opioid consumption, emergency department visits, and interventional pain procedures. This study shows substantial improvements in patient outcomes and decreased healthcare costs.

Keywords:
chronic low back paincost-effectivenessemergency departmentshealthcare utilizationopioid useoutpatient visitsspinal cord stimulation

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Area of Science:

  • Pain Management
  • Neuromodulation
  • Health Economics

Background:

  • Chronic pain significantly impacts patients' quality of life and incurs substantial healthcare costs.
  • Spinal Cord Stimulation (SCS) is an established treatment for chronic pain, but its impact on overall healthcare utilization requires further investigation.
  • High-frequency (10 kHz) SCS offers a potential alternative for managing chronic pain and reducing associated healthcare resource consumption.

Purpose of the Study:

  • To evaluate the impact of 10 kHz SCS on healthcare utilization (HCU) in patients with chronic pain.
  • To assess changes in opioid consumption, emergency department (ED) visits, and interventional pain procedure visits post-SCS implantation.
  • To analyze real-world data on HCU trends associated with 10 kHz SCS across various pain etiologies.

Main Methods:

  • Retrospective, single-center observational study of 160 patients who received 10 kHz SCS implants.
  • Assessed HCU metrics including opioid consumption (MME), ED visits, and office visits for interventional pain procedures.
  • Compared HCU data during the 12 months preceding and following SCS implantation.

Main Results:

  • Statistically significant reductions in all HCU domains were observed post-SCS implantation.
  • Mean opioid consumption (MME) decreased from 51.05 to 26.52 (78.2% reduction, p < 0.0001), with 91.5% achieving minimally clinically important difference (MCID).
  • Mean ED visits decreased from 0.12 to 0.03 (p < 0.01), and office visits for interventional pain procedures decreased from 1.39 to 0.28 (p < 0.0001).

Conclusions:

  • 10 kHz SCS significantly reduces healthcare utilization in patients with chronic pain.
  • The findings support the cost-effectiveness of 10 kHz SCS by demonstrating reductions in opioid use and procedural interventions.
  • This study provides the largest real-world dataset to date collectively analyzing opioid use, ED visits, and outpatient procedures in conjunction with 10 kHz SCS.