Association between Preoperative C-Reactive Protein-to-Albumin Ratio and Mortality after Plastic and Reconstructive Surgery
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View abstract on PubMed
Summary
This summary is machine-generated.The C-reactive protein (CRP)-to-albumin ratio (CAR) can predict one-year mortality in plastic surgery patients. A high CAR indicates increased risk, outperforming other common prognostic markers.
Area Of Science
- Plastic and Reconstructive Surgery
- Surgical Oncology
- Inflammatory Markers
Background
- Prognostic markers are understudied in plastic and reconstructive surgery.
- Preoperative inflammatory markers may predict patient outcomes.
Purpose Of The Study
- Evaluate the prognostic value of the C-reactive protein (CRP)-to-albumin ratio (CAR).
- Compare CAR with neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and modified Glasgow prognostic score (mGPS).
Main Methods
- Retrospective analysis of 2519 patients undergoing plastic and reconstructive surgery (Jan 2011-July 2019).
- Utilized receiver operating characteristic (ROC) curve analysis to determine CAR threshold.
- Assessed one-year and overall mortality rates.
Main Results
- CAR demonstrated superior predictive ability (AUC=0.803) compared to NLR, PLR, and mGPS.
- High CAR (threshold 1.05) was significantly associated with increased one-year mortality (10.9% vs 1.3%).
- Hazard ratio for mortality in high CAR group was 2.88 (95% CI, 2.17-3.83; p < 0.001).
Conclusions
- High preoperative CAR is a significant predictor of one-year mortality in plastic and reconstructive surgery.
- CAR offers a valuable prognostic tool in this patient population.
- Further research into prognostic markers in plastic surgery is warranted.
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