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Acute Appendicitis in the Elderly: A Nationwide Retrospective Analysis

Malkiely Gal¹, Paran Maya², Kobo Ofer³

¹Division of Surgery, Hillel Yaffe Medical Center, Hadera 38100, Israel.

Journal of Clinical Medicine

|April 13, 2024

Summary

Older adults have a higher rate of complicated appendicitis and associated infections. Comorbidities influence infection risk differently across age groups, highlighting unique challenges in geriatric appendicitis care.

Area of Science:

Geriatric Medicine
Surgical Outcomes
Infectious Disease Epidemiology

Background:

Acute appendicitis (AA) in individuals over 60 is understudied.
Comorbidities may influence AA presentation and outcomes in older adults.

Purpose of the Study:

To assess AA characteristics in patients over 60.
To evaluate the impact of comorbidities on AA outcomes in older patients.

Main Methods:

Retrospective analysis of the American National Inpatient Sample (2016-2019).
Comparison of AA characteristics between patients younger and older than 60 years.

Main Results:

Older patients (27.5%) had higher rates of complicated appendicitis, superficial wound infection, systemic infection, and mortality.
Comorbidities presented different risk factors for infections in younger versus older patients.
Heart failure and obesity were significant risk factors for infections in older adults.

Conclusions:

This study reveals a higher incidence of AA in older individuals than previously reported.
Comorbidities differentially impact infection risks in older adults with AA.
Geriatric appendicitis requires tailored management strategies considering age-related risk factors.

Keywords:

acute appendicitis age-related complications clinical outcomes comorbidities elderly

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