Related Experiment Video
Updated: Jun 28, 2025
08:48
Flow Cytometric Analysis of Biomarkers for Detecting Human Sperm Functional Defects
Published on: April 21, 2022
2.4K
Introducing a New Smartphone Applied Semen Analyzer, SpermCell™: A Cross-Sectional Validation Study with a
Muhammet Murat Dincer1, Serhat Yentur1, Aykut Colakerol1
1Department of Urology, Bagcilar Training and Research Hospital, Istanbul 34200, Turkey.
Diagnostics (Basel, Switzerland)
|April 13, 2024
Summary
A new smartphone semen analyzer, Sperm Cell™, shows comparable diagnostic accuracy to standard methods for sperm count and motility. This user-friendly device offers a reliable at-home testing option for initial infertility assessments.
Area of Science:
- Andrology
- Reproductive Medicine
- Medical Diagnostics
Background:
- Standard semen analysis methods can suffer from inter-observer variability and human error.
- Novel diagnostic tools are needed to improve accuracy and accessibility in semen analysis.
- Smartphone-based applications offer potential for point-of-care testing.
Purpose of the Study:
- To introduce and evaluate the diagnostic efficacy of a novel smartphone-applied semen analyzer, Sperm Cell™.
- To compare the performance of Sperm Cell™ against the standard manual semen analysis method.
- To assess the user-friendliness of the Sperm Cell™ analyzer for both technicians and patients.
Main Methods:
- A cross-sectional study involving 102 men and their semen samples.
- Comparison of semen parameters (sperm count, motile sperm count, percentage of motile sperm) using standard manual analysis, Sperm Cell™ by technicians, and Sperm Cell™ by patients.
- Correlation analysis between Sperm Cell™ results and standard methods.
- Evaluation of diagnostic accuracy, sensitivity, and specificity for oligospermia and asthenozoospermia.
- User-friendliness assessment via a mini-questionnaire.
Main Results:
- Semen parameters determined by Sperm Cell™ (technician and patient use) were statistically similar to the standard manual method (p > 0.05).
- High correlation coefficients (up to 0.85) were observed between Sperm Cell™ and standard analysis.
- The device demonstrated substantial diagnostic accuracy, sensitivity, and specificity in identifying oligospermia and asthenozoospermia.
- User-friendliness was confirmed through participant feedback.
Conclusions:
- The smartphone-applied Sperm Cell™ analyzer is a valuable tool for determining major semen parameters with acceptable diagnostic accuracy.
- The device is user-friendly and suitable for at-home point-of-care testing.
- Sperm Cell™ can serve as an efficient initial assessment method for couples experiencing infertility concerns.
