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Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...

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Related Experiment Video

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Quantifying the Modulation of Elastase Enzyme Activity Through Colorimetric Analysis

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Research Progress on Bioactive Factors against Skin Aging.

Xin He^1,2,3, Xinyu Gao^1,3, Yifan Guo^1,2,3

¹State Key Laboratory of Chemical Oncogenomics, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.

International Journal of Molecular Sciences

|April 13, 2024

Summary

Bioactive factors from natural sources show promise for anti-aging skin care. These compounds, including peptides and antioxidants, help improve skin health by boosting collagen and enhancing the skin barrier.

Keywords:

biological activity factor collagen enzyme oxidative stress polypeptide skin aging

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Area of Science:

Dermatology
Cosmetic Science
Natural Product Chemistry

Background:

Skin aging is influenced by environmental factors like UV radiation and oxidative stress.
Bioactive factors, including peptides and secondary metabolites, are investigated for anti-aging properties.
Natural sources offer a rich reservoir of compounds for skin health.

Purpose of the Study:

To review recent advancements in bioactive factors for combating skin aging.
To focus on the sources, mechanisms of action, and therapeutic potential of these factors.
To synthesize current research for developing innovative anti-aging skincare.

Main Methods:

Literature review of recent studies on bioactive factors and skin aging.
Analysis of mechanisms of action, including collagen synthesis and skin barrier function.
Emphasis on collagen peptides, antioxidants, and herbal extracts.

Main Results:

Bioactive factors demonstrate effectiveness in promoting collagen synthesis.
These compounds enhance skin barrier function, mitigating aging signs.
Natural extracts and peptides show significant therapeutic potential.

Conclusions:

Continued exploration of bioactive compounds is crucial for anti-aging skincare innovation.
Bioactive factors offer a promising avenue for improving skin health and aesthetics.
Further research can lead to revolutionary advancements in dermatological treatments.