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Updated: Jun 28, 2025

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Medication "underuse" headache.

Wanakorn Rattanawong¹, Alan Rapoport², Anan Srikiatkhachorn¹

¹Faculty of Medicine, King Mongkut's Institute of Technology Ladkrabang, Bangkok, Thailand.

Cephalalgia : an International Journal of Headache

|April 13, 2024

Summary

This summary is machine-generated.

Underuse of migraine medications, both acute and preventive, contributes to migraine progression. Optimizing medication use can prevent chronic migraine and improve treatment outcomes.

Keywords:

acute medication inadequate migraine preventive medication underuse

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Area of Science:

Neurology
Pharmacology
Pain Management

Background:

Migraine progression is linked to risk factors like medication underuse, which is inadequately explored.
Suboptimal medication use risks migraine chronification without updated prescribing guidelines.

Purpose of the Study:

To review evidence on the underuse of acute and preventive migraine medications.
To define medication underuse, including ineffective use, underutilization, poor timing, and patient dissatisfaction.

Main Methods:

Comprehensive literature review of studies on migraine medication underuse.
Analysis of factors contributing to acute and preventive medication underuse.

Main Results:

Underuse of acute medications (late use, incorrect type, discontinuation) and preventive medications (inefficacy, side effects) drives migraine progression.
Anti-calcitonin gene-related peptide (CGRP) therapies show promise but early initiation is key.
Patient adherence and medication effectiveness are crucial for preventing chronification.

Conclusions:

Medication underuse is a significant, underrecognized factor in migraine chronification.
Optimizing acute and preventive migraine medication use can prevent progression and improve patient outcomes.