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Related Experiment Video

Updated: Jun 28, 2025

DIPLOMA Approach for Standardized Pathology Assessment of Distal Pancreatectomy Specimens

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Published on: February 1, 2020

Impact of surgical proximal and distal margins on the recurrence of resectable colon cancer: a single-center

Tetsuro Kawazoe¹, Satoshi Toyota², Ryota Nakanishi²

¹Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-Ku, Fukuoka-City, Fukuoka, 812-8582, Japan. kzoe922@gmail.com.

|April 13, 2024

Summary

For pT4 colon cancer, maintaining surgical resection margins of at least 7 cm is crucial. Wider margins are linked to reduced recurrence and improved relapse-free survival in these patients.

Keywords:

Colon cancer Distal margin Proximal margin Recurrence Relapse free survival

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Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

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Published on: September 27, 2024

Area of Science:

Oncology
Surgical Oncology
Gastrointestinal Surgery

Background:

Surgical resection margins are critical in colon cancer treatment.
The impact of specific margin lengths on colon cancer recurrence remains under-investigated.

Purpose of the Study:

To investigate the effect of surgical resection margins on the prognosis of resectable colon cancer.
To determine the optimal resection length influencing recurrence in colon cancer patients.

Main Methods:

Retrospective analysis of 579 resectable colon cancer patients.
Assessment of the association between resection margin and recurrence across oncological statuses.
Analysis of resection length's impact on recurrence.

Main Results:

Patients with pT4 colon cancer and margins >7 cm showed a trend towards fewer recurrences and longer relapse-free survival (RFS).
A margin <7 cm was an independent risk factor for RFS in pT4 colon cancer (HR, 2.65).
No correlation between resection margins and recurrence was found concerning lymph node metastasis or tumor location.

Conclusions:

A resection margin of at least 7 cm is recommended for patients with pT4 colon cancer.
Optimizing surgical margins may improve outcomes for advanced colon cancer stages.