Prognosis prediction of procalcitonin within 24 h for acute diquat poisoning
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View abstract on PubMed
Summary
This summary is machine-generated.Procalcitonin (PCT) levels within 24 hours of poisoning can predict outcomes in acute diquat poisoning patients. Higher PCT levels indicate a poorer prognosis, offering a valuable tool for patient management.
Area Of Science
- Toxicology
- Clinical Chemistry
- Medical Prognostics
Background
- Acute diquat poisoning presents a significant health risk.
- Early prognostic markers are crucial for managing poisoning cases.
- Procalcitonin (PCT) is a potential biomarker for bacterial infections and inflammation.
Purpose Of The Study
- To evaluate the predictive capability of procalcitonin (PCT) levels within 24 hours post-poisoning for the prognosis of acute diquat poisoning.
- To compare PCT's predictive value against other clinical and biochemical markers.
Main Methods
- A retrospective study was conducted on 45 patients with acute diquat poisoning.
- Data collected included procalcitonin levels within 24 hours of poisoning.
- Prognostic outcomes (survival vs. non-survival) were analyzed in relation to PCT levels and other variables.
Main Results
- Non-survival patients exhibited significantly higher maximum PCT levels within 24 hours post-poisoning compared to survivors (P < 0.001).
- Maximum PCT levels demonstrated a strong predictive value (AUC = 0.905), comparable to blood lactate (AUC = 0.904).
- PCT's predictive accuracy surpassed that of ingested quantity, serum creatinine, and APACHE II score.
Conclusions
- The maximum procalcitonin (PCT) level within 24 hours after acute diquat poisoning serves as a valuable predictor of patient prognosis.
- PCT measurement offers a reliable and accessible tool for assessing the severity and predicting outcomes in acute diquat poisoning.
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