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Risk Factors of Seizure in Childhood Shigellosis

Abolfazl Mahyar1, Shifteh Mahyar1, Sonia Oveisi1

  • 1Qazvin Children Hospital, Qazvin University of Medical Sciences, Qazvin, Iran.

Iranian Journal of Child Neurology
|April 15, 2024
PubMed

Insights

Identifying risk factors for seizures in childhood shigellosis is crucial. A history of febrile seizures, fever, and hyponatremia are key predictors of seizures in children with shigellosis.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Neurology

Background:

  • Shigellosis is a frequent cause of bacterial diarrhea in children.
  • Seizures are a common complication of shigellosis, necessitating identification of associated risk factors.

Purpose of the Study:

  • To determine the risk factors associated with seizures in children diagnosed with shigellosis.

Main Methods:

  • A study involving 224 children with shigellosis was conducted, comparing 63 cases with seizures to 161 controls without seizures.
  • Variables analyzed included age, gender, clinical symptoms, and laboratory findings.
  • Logistic regression analysis was employed to identify significant risk factors for seizures.

Main Results:

  • Significant differences between seizure and control groups were noted in age, history of febrile convulsions, bloody diarrhea, fever, diarrhea duration, abdominal pain, BUN levels, hyponatremia, hypocalcemia, and stool red blood cell count.
  • Logistic regression identified a history of febrile seizure, fever, and hyponatremia as significant risk factors for seizures in shigellosis.

Conclusions:

  • Childhood shigellosis with risk factors like prior febrile seizures, fever, and hyponatremia requires prompt diagnosis and treatment to mitigate seizure risk.
Abstract

Keywords:
ChildrenSeizureShigellosis

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