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ICTV Virus Taxonomy Profile: Fusariviridae 2024
Sotaro Chiba1, Nobuhiro Suzuki2, Leonardo Velasco3
1Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-0861, Japan.
The Journal of General Virology
|April 15, 2024
Summary
The Fusariviridae virus family features single-segment, positive-sense RNA genomes. These viruses, lacking apparent virions, possess unique RNA-directed RNA polymerase and RNA helicase proteins.
Area of Science:
- Virology
- Molecular Biology
- Taxonomy
Background:
- Fusariviridae is a family of viruses with mono-segmented, positive-sense RNA genomes.
- Genomes range from 5.9-10.7 kilobases and are typically bicistronic, though some possess up to four open reading frames (ORFs).
Purpose of the Study:
- To summarize the International Committee on Taxonomy of Viruses (ICTV) report on the Fusariviridae family.
- To provide an overview of the genomic characteristics and unique features of Fusariviridae.
Main Methods:
- Review and synthesis of information from the ICTV report.
- Analysis of genomic features including segmentation, sense, size, and ORFs.
Main Results:
- Fusariviridae genomes are mono-segmented, positive-sense RNA, 5.9-10.7 kb in size.
- Most genomes are bicistronic; the 5 -proximal ORF encodes RNA-directed RNA polymerase (RdRP) and RNA helicase (Hel) domains.
- Fusarivirids do not appear to form virions.
Conclusions:
- Fusariviridae represents a distinct viral family with unique genomic and structural characteristics.
- Further research is needed to understand the protein encoded by the second ORF in bicistronic genomes.
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