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Updated: Jun 28, 2025

Protocol for Recombinant RBD-based SARS Vaccines: Protein Preparation, Animal Vaccination and Neutralization Detection
Published on: May 2, 2011
[Position statement of the Spanish Society of Nephrology on the SARS-CoV-2 vaccines]
Emilio Sánchez-Álvarez1,2, Borja Quiroga3,2, Patricia de Sequera4,2
1Servicio de Nefrología, Hospital Universitario de Cabueñes, Gijón, España.
Abstract:
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide over the last year causing more than one million deaths. Several treatments have tried to modify the natural history of the coronavirus disease 2019 (COVID-19) but only corticosteroids have demonstrated to be effective in moderate or severe affectation. In that situation, the development of vaccines for preventing the SARS-CoV-2 infection has focused the attention of the scientific community. At present, available messenger RNA-based technology vaccines have received the approval of local and international sanitary authorities. In this position statement, the Spanish Society of Nephrology wants to state that patients with chronic kidney disease and healthcare workers are at high-risk for contagion and complications of COVID-19 so they must have priority in the vaccine administration.
Insights
Patients with chronic kidney disease and healthcare workers are at high risk for COVID-19 complications. The Spanish Society of Nephrology recommends prioritizing these groups for messenger RNA vaccine administration.
Area of Science:
- Nephrology
- Infectious Diseases
- Vaccinology
Context:
- The global spread of SARS-CoV-2 has led to significant mortality.
- Corticosteroids are effective for moderate to severe COVID-19.
- Vaccine development is a primary focus for SARS-CoV-2 prevention.
Purpose:
- To outline the Spanish Society of Nephrology's position on COVID-19 vaccination.
- To identify high-risk populations for SARS-CoV-2 infection and complications.
Summary:
- Messenger RNA (mRNA) vaccines are approved and available.
- Patients with chronic kidney disease (CKD) face elevated risks from SARS-CoV-2.
- Healthcare workers are also identified as a high-risk group.
Impact:
- Recommends prioritizing CKD patients and healthcare workers for vaccination.
- Highlights the critical role of vaccination in mitigating COVID-19 impact on vulnerable populations.
- Advocates for equitable vaccine distribution strategies based on risk assessment.
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