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Experimental and Imaging Techniques for Examining Fibrin Clot Structures in Normal and Diseased States
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Fibrinolysis shut down in COVID-19 patients: Report on two severe cases with potential diagnostic and clinical
Tamam Bakchoul1, Stefanie Hammer1, Peter Lang2
1Transfusion Medicine, University Hospital of Tübingen, Tübingen, Germany.
Thrombosis Update
|April 15, 2024
Abstract:
•To date most reports on COVID-19 associated coagulopathy focused an increased activation of the plasmatic coagulation system.•Using a novel method to assess clot lysis we observed abnormalities in fibrinolysis in COVID-19 infection.•Our finding suggests that fibrinolysis system may contribute to the procoagulatory status in COVID-19 patients.
Keywords:
COVID-19CT, cloting timeCoagulationEX-Test, extrinsic testFibrinolysisLT, lysis timeM, maleMCF, maximum clot firmnessML, maximum clot lysisPLT, platelet countPT, prothrombin timeSOFA, Sepsis-related organ failure assessment scoreTPA, tissue plasminogen activatoraPTT, activated partial thromboplastin timey, yearsRelated Concept Videos
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